2-(2-Oxo-2-phenylethyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

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2-(2-Oxo-2-phenyl­ethyl)-1,2-benziso­thia­zol-3(2H)-one 1,1-dioxide

In the title compound, C(15)H(11)NO(4)S, the benzothia-zole unit is essentially planar [maximum deviation = 0.0644 (14) Å for the N atom] and forms a dihedral angle 54.43 (6)° with the phenyl ring. In the crystal structure, weak bifurcated C-H⋯O hydrogen bonds involving the carbonyl O atoms as acceptors result in R(2) (2)(7) ring motifs.

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synthesis and evaluation of anti-acetylcholinesterase activity of 2-(2-(4-(2-oxo-2-phenylethyl)piperazin-1-yl) ethyl)isoindoline-1,3-dione derivatives with potential anti-alzheimer effects

objective(s): alzheimer's disease (ad) is a neurodegenerative disorder in elderly patients. decrease in cholinergic neurotransmission is the main known cause in the pathophysiology of the disease. improvement and potentiation of the cholinergic system could be beneficial for treatment of the ad. acetylcholinesterase inhibitors such as donepezil can enhance the duration of action of acetylc...

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2-(2-phenylethyl)chromones from Chinese eaglewood.

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2-Oxo-2-(2-thien­yl)acetic acid

The structure of the title compound, C(6)H(4)O(3)S, displays inter-molecular hydrogen-bonding dimers. The structure exhibits a thienyl-ring flip disorder of the main mol-ecule [occupancy ratio = 91.3 (2):8.7 (2)].

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2010

ISSN: 1600-5368

DOI: 10.1107/s1600536810005404